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Mild IVF vs. Conventional IVF: What’s the Difference?

October 25, 2024
Mild IVF vs. Conventional IVF: What’s the Difference?

With advancements in medical science, couples who cannot conceive can experience parenthood through IVF or In-vitro fertilisation. However, the evolution of IVF approaches is focusing on getting positive results in an optimized way. Hence, couples who are interested in the IVF process might find themselves in a dilemma about which approach is better, got instance, mild IVF vs. conventional IVF. 

If you are looking for an IVF in North Delhi, you must understand that conventional IVF uses high-dose hormone stimulation to encourage the production of a large number of eggs (10-15 eggs for retrieval) in a single cycle. The number of eggs increases, which increases the chances of fertilization. 

However, in mild IVF is in contrast with conventional IVF, as it requires a low dose of fertility drugs and aims for fewer but high-quality eggs (3-8 eggs for retrieval). Let’s understand more about the mild IVF vs. conventional IVF, and what factors decide which method should be preferred. 

What is Conventional IVF?

Conventional IVF is the most common way of fertility treatment and has been practised for many years. The process involves the use of a large number of drugs, usually gonadotropins (FSH and LH), that stimulate the ovaries to release several eggs in one cycle for a period of 10-14 days. 

The intent is to retrieve as many eggs as possible to make as many embryos, increasing the chances of conception. One cycle of IVF takes around 2-3 weeks, and it is suitable for women with high ovarian reserve. 

Traditional IVF allows the collection of a higher number of eggs, which makes it more successful, especially for women under 35. The success rate ranges from 25% to 40%.

What is Mild IVF?

The relatively new concept in fertility treatment is Mild IVF, minimal stimulation IVF, or Gentle IVF. It uses a gentler ovarian stimulation protocol that requires low doses of fertility medications. The process is highly safe as it reduces the risk of hyperstimulation and lowers the cost of medications required.

This method works with the body’s natural cycle rather than against it, which results in the collection of higher-quality eggs. The treatment time for mild IVF is two weeks, and it has equivalent success rates as conventional IVF. 

Although the number of eggs retrieved is lower than that in standard IVF, mild IVF can also be quite successful, primarily where the woman has healthy ovaries. Nevertheless, mild IVF seems to be more appropriate for women who cannot tolerate high doses of hormones or have low levels of ovarian reserve. 

Which is Better: Mild or Conventional IVF?

Traditionally, the focus of IVF treatment has been on collecting more eggs to maximise success rates. The ovary produces several follicles that are capable of producing and releasing eggs in a normal cycle. At some point, one follicle becomes dominant and uses the body’s resources to grow and release eggs, and the other follicles will shrink and ultimately die. 

The stimulating drugs used in conventional IVF don’t create new follicles; rather, they encourage the other follicles to grow instead of shrinking and dying. However, the body does not choose these as the front runners. This indicates that collecting more eggs doesn’t guarantee success because the final number of eggs that are actually viable and will create a baby is the same, regardless of the dose of fertility drugs. 

Especially in the cases of women who have gone through several IVF cycles and failed, a high dose of stimulation drug will not be helpful as extra follicles cannot be created. 

That’s why new approaches, like mild IVF, focus on the follicle, which is selected by the body to produce eggs and collect them at the right time to increase the chances of successful fertilization. In mild IVF, there is no down-regulation or ovarian suppression, which leads to temporary menopause. The low-dose of stimulating hormone gently stimulates the ovary to produce few but high-quality eggs, which leads to a more natural cycle with less hormonal impact. 

Wrapping up, 

When it comes to understanding which method to choose, a number of factors come into play. For instance, ovarian reserve, age, ovarian response to stimulation, medical conditions, fertility goals, and personal preference will affect the decision on which method to choose for IVF. 

If you are diagnosed with PCOS (Polycystic Ovarian Syndrome) or want to take a lower amount of drugs and reduce the physical and emotional burden that comes with conventional IVF, then you can go with mild IVF. 

However, if the ovarian reserve is diminished, doctors might suggest conventional IVF. A consultation with a doctor will clear all the clouds of confusion, and Nandi IVF, a reliable IVF in North Delhi with an over 80% IVF fertility success rate, can help! 

We strive to make couples’ dreams of becoming parents come true. At the IVF clinic in Pitampura, we are a team of experienced doctors and fertility specialists committed to providing you with the best possible results. Schedule an appointment today to get expert advice.

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