Understanding the Common Reasons for Failed IVF Cycles

March 15, 2024
Understanding the Common Reasons for Failed IVF Cycles

In-vitro fertilization (IVF) is a popular assisted reproductive procedure that allows many couples to fulfill their desire of having a child. While IVF might be incredibly successful, it can often fail, causing disappointment and anger. Several variables can lead to IVF failure, and understanding these causes can help people and couples make more educated decisions, thereby increasing their chances of success.

With advances in reproductive technology and sufficient help from fertility professionals, many couples may overcome these obstacles and realize their dream of parenting. This blog explores the common roadblocks in detail.

Reasons for IVF Failure

Before learning why an IVF cycle fails, everyone should understand that no matter what you do, the success rate of IVF cannot be guaranteed. The average success rate of IVF globally is 35-40%. If an IVF facility promises a 100% success rate, it’s advisable to seek a second opinion from a facility that provides realistic expectations, such as the best IVF in Delhi. Let us briefly go over the eight elements that influence your IVF results.

Poor egg quality

Poor egg quality might be the leading cause of IVF failure. The quality and quantity of their eggs diminish as the women age. Despite advancements in testing, low egg quality can impact the IVF cycle, a concern addressed by the IVF treatment in Delhi.

Poor Sperm Health

Poor sperm health, such as poor sperm count and motility, can significantly impair IVF outcomes. If you or your spouse are experiencing similar issues, there are therapies available to help you manage them. Treatments are available to address these issues, provided by IVF specialists in Delhi.

Oocyte Age

As women age, the quality and number of eggs diminish. It has a direct impact on the implantation rates and, ultimately, the IVF success rate. As a result, women under the age of 35 might have a 40% success rate, compared to only 15% after the age of 40, highlighting the expertise provided by IVF doctors in Delhi.

Chromosomal abnormalities

It is one of the primary reasons that IVF rounds might fail. During fertilization, chromosomal alterations occur. If a chromosomal defect (embryonic arrest) occurs, the body may reject the embryo, resulting in unsuccessful IVF. Couples should be aware that only 25% of oocytes reach the ultimate stage, which may result in pregnancy.

No reaction to IVF injection

When other factors like egg quality and quantity are not a concern, IVF injections or drugs can impact IVF cycle outcomes. In certain cycles, the body does not respond to IVF injections, and doctors are unable to finish the ovarian stimulation procedure. This is where the experience at the best IVF centre in Delhi comes into play.

Inappropriate Laboratory Conditions

Initially, the lab operates like a woman’s uterus. Everything within the lab is carefully monitored to achieve optimal outcomes during an IVF cycle. Poor lab conditions can reduce IVF success rates. Make sure you find the finest IVF facility that focuses on these small but significant elements during the cycle.

Genetic and chromosomal causes

The most common cause of IVF failure is chromosomal abnormalities. The incidence of such defects in human eggs began to rise in the mid-1930s. IVF treatment in older women: Women over the age of 40 are more likely to have low-quality eggs with chromosomal abnormalities, resulting in a reduced IVF success rate. According to research, sperm have considerably more defects than female eggs, which may be one of the causes of IVF failure.

Unhealthy lifestyle

Another common but crucial element influencing IVF success rates is your lifestyle. Obesity, underweight, nutritional difficulties, stress, smoking, and drinking can all have a negative impact on your chances of becoming pregnant. Quit smoking now since it reduces egg quality and lowers sperm quantity and rate.

Improper egg retrieval and transport.

Every phase of the IVF process is critical. If activities such as egg collection and embryo transfer are not carried out correctly, the IVF success rate might suffer significantly. 

What would be your next step?

Unsuccessful implantation is not the end of the road. Following the failure of the IVF, the following options may be considered:

  • Another attempt at IVF may be an option. This can be accomplished by consulting with your doctor, understanding the causes of failure, and perhaps attempting another re-implantation with a higher likelihood of successful pregnancy.
  • Some women who are unable to carry a viable embryo (for a variety of reasons) might choose a gestational carrier, who can offer an early environment for embryo growth.
  • Having a donor who can contribute eggs or sperm can be a solution for women and men who are concerned about egg or sperm quality.

The Final Word

IVF is a difficult and multifaceted procedure that requires a variety of components to be successful. Understanding the primary causes of IVF failure can help couples and individuals collaborate closely with their reproductive professionals to address any possible problems. While not all factors can be managed, living a healthy lifestyle, following pharmaceutical instructions, and obtaining emotional support can help to improve results. Every fertility journey is unique, and it’s crucial to realize that IVF failures do not determine one’s odds of becoming a parent.

Consult with your doctor at Nandi IVF, the best IVF centre in Delhi, to discuss adjustments for better results. Our IVF specialist in Delhi can also provide insights into IVF costs and processes. Contact us today to learn more.

Sr. IVF Specialist & Medical Director at NANDI IVF
Dr. Payal Bajaj is an experienced Obstetrician & Gynecologist with over 20 years of experience in the discipline. She is a Reproductive Endocrinologist & Infertility Specialist. She has Done MBBS From the Renowned Lady Hardinge Medical College. DGO from the prestigious VMMC & Safdarjang Hospital, DMAS From World Laparoscopy Hospital.

She has Completed Her esteemed ASPIRE -ISAR Fellowship in the field of Reproductive Medicine from AFGC, Delhi And St' Mother's Hospital Japan.She has also been trained from the University of KEIL Germany. She has won various academic awards all through her academic career.
Dr. Payal Bajaj

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