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What is Intracytoplasmic Sperm Injection (ICSI)?

intracytoplasmic sperm injection (icsi)

What is Intracytoplasmic Sperm Injection (ICSI)?

ICSI is an innovative method that has revolutionized the treatment of infertility by offering a solution to couples facing male infertility problems. Before a man’s sperm can fertilize a woman’s egg, the head of the sperm must first attach to the outside of the egg. After fixation, the sperm penetrates through the outer layer into the cytoplasm of the egg, thus, fertilization takes place. 

Sometimes, for various reasons, sperm cannot pass through the outer layer. The outer layer of the egg or ovum can be thick or hard to penetrate, and the sperm cannot swim. In these cases, a procedure called intracytoplasmic sperm injection (ICSI) is performed by IVF Specialists in Delhi to help fertilize the egg. Let us learn more about ICSI.

What is ICSI?

Intracytoplasmic sperm injection (ICSI) is an advanced assisted reproductive technology (ART) procedure used in infertility treatment to resolve male infertility and promote fertilization. This involves the precise placement of a single sperm into the cytoplasm of the egg. The egg carries out fertilization. ICSI is usually performed as part of IVF treatment in Delhi and is designed to increase the chances of pregnancy when traditional fertilization methods may be less successful due to male infertility problems.

Why do you need ICSI?

ICSI at the best IVF centre In Delhi helps overcome fertility problems such as:

  • The male partner produces too little sperm for artificial insemination (IUI) or IVF. 
  • The sperm may not move normally. 
  • Difficulty for the sperm to fertilize the egg. 
  • A blockage in the male reproductive tract interferes with the release of sperm. 
  • Eggs cannot be fertilized with traditional IVF regardless of sperm status. 
  • Eggs matured in vitro are used. 
  • Usage of pre-frozen eggs.

How ICSI is performed

The ICSI procedure at the best IVF centre in Delhi involves the following steps:

Before ICSI procedure 

Before performing ICSI, your IVF doctor in Delhi must collect eggs and sperm. To collect the eggs, the following steps are taken:

  • Ovulation induction (also called ovarian stimulation): The donor receives injections of medication for 8 to 14 days. This stimulates the ovaries to release several eggs at once to mature.
  • Egg retrieval: Your doctor uses transvaginal ultrasound technology to insert a thin needle through the vaginal wall into the ovaries. This step is performed under light anesthesia, so there is no pain.

If frozen sperm are not used, the sperm collection is done on the same day as the egg retrieval.

During ICSI procedure 

During ICSI, your IVF specialist in Delhi will:

  • Use a pipette (a small glass tube with a suction cup) to hold the egg in a laboratory dish. 
  • A single sperm is immobilized and collected using a thin needle. 
  • A needle is inserted into the egg to reach the cytoplasm. 
  • Sperm enters the cytoplasm. 
  • The needle is then taken out of the egg.

After ICSI procedure

After ICSI, your doctor at the best IVF in Delhi will check the fertilized egg in a laboratory to monitor signs of successful fertilization. 

  • Within 5 to 6 days after the ICSI procedure, a healthy fertilized egg must divide into cells to form a blastula, which the doctor assesses. 
  • Embryo transfer occurs five to six days after the egg retrieval procedure, but the transfer is usually delayed by months or years. 
  • Your doctor will discuss with you the timing of the embryo transfer. 
  • Using ultrasound technology, the doctor inserts a catheter (a long, thin tube) into the vagina and places the embryo in the uterus. 
  • For pregnancy to occur, the embryo must implant (attach) to the uterus. 

IVF doctors in Delhi recommend waiting at least two weeks before taking a pregnancy test.

The success rate of intracytoplasmic sperm injection (ICSI)

The Centers for Disease Control and Prevention (CDC) does not have data on ICSI success rates, but other fertility clinics report fertilization rates of 70 to 80 percent for injected eggs.

About 6 out of 10 IVF procedures involve ICSI. The chances of pregnancy success with ICSI are the same as with conventional IVF. According to the Cleveland Clinic, it is estimated that 50 to 80 percent of ICSI attempts lead to fertilization.

Final Words,

For couples who are having trouble conceiving, the doctor may recommend intracytoplasmic sperm injection (ICSI). This type of in vitro fertilization (IVF) is helpful in cases of male infertility. However, it is necessary to talk to your healthcare provider at the IVF centre in Delhi about whether ICSI is the best fertility treatment for you. 

Is it difficult to get pregnant because of male infertility? Find hope with Nandi IVF’s advanced ICSI treatment. Our team of experts specializes in providing customized solutions for couples facing infertility issues. We want to help you fulfil your dream of becoming a parent with our cutting-edge technology. Take the first step towards a better future with the best IVF centre in Delhi. Book your consultation with Nandi IVF today.

Male Infertility: Symptoms, Causes, and Treatment

Infertility can be a distressing issue for many couples who wish to start a family. While both male and female fertility issues contribute to this problem, it’s estimated that male infertility is the primary or contributing cause in around 30-50% of cases. 

With the advancements in reproductive technologies, facilities like the Best IVF in Delhi have become beacons of hope for countless individuals. This article delves into the symptoms, causes, and treatments of male infertility, providing a guiding light for those navigating this complex path.

What is Male Infertility? 

Male infertility refers to a male’s inability to lead to a pregnancy in a fertile female. It is commonly diagnosed when abnormal semen quality, function, or production impairs the probability of sperm fertilizing the egg. It’s a condition that impacts an estimated one in every six couples, with male factors accounting for about 50% of all infertility cases

Common Symptoms

There are no obvious signs of male infertility other than the inability to conceive a child. Some subtle signs pointing to potential male fertility problems include:

– Changes in sexual desire

– Erectile dysfunction  

– Issues with ejaculation, including painful ejaculation or blood in the semen

– Testicular pain or swelling

– Recurrent respiratory infections

– Decreased facial or body hair 

Paying attention to such symptoms and seeking timely medical assistance can help identify and address the underlying conditions early.

Causes of Male Infertility

Male infertility has numerous possible causes, spanning lifestyle factors, anatomical problems, genetic conditions, hormonal imbalances, and environmental exposures.

Hormonal disorders like low testosterone, estrogen imbalance, and pituitary or thyroid diseases account for some fertility hurdles. Physical causes range from varicocele, cystic fibrosis, infections, obstructions in the reproductive tracts, medications to prior surgeries.

Lifestyle habits like heavy alcohol consumption, smoking, use of anabolic steroids, stress, and obesity also deteriorate sperm quality and fertility rates. Environmental toxins, including pesticides, lead, radiation, or heat exposure too, can lead to reduced sperm production and mobility.

In some cases, genetic causes like chromosomal defects, Y chromosome deletion, or issues like Klinefelter syndrome are responsible. Identifying the cause is crucial for effective treatment, necessitating a visit to a reputed Ivf Specialist In Delhi.

Diagnosis

Diagnosing male infertility involves examinations of one’s medical history, genetic conditions, and infection status, as well as assessments like:  

– Physical examination

– Semen analysis 

– Blood tests to evaluate hormone levels

– Imaging tests like scrotal ultrasound

– Genetic testing  

Treatment Options

Treatments vary based on the underlying cause but often include:

  • Medical Treatments: Hormone replacements or medications to address specific deficiencies or issues like gonadotropin shots.
  • Surgical Treatments: Procedures to rectify physical impediments like varicocele.
  • Assisted Reproductive Technologies (ART): ART, which includes In vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI), has markedly improved fertility success rates nowadays by enabling ways for sperm to fertilize the egg outside the body in a lab environment.
  • Lifestyle Adjustments: Lifestyle modifications regarding diet, exercise, stress reduction, and avoiding smoking or alcohol abuse also help boost natural fertility.

Facilities offering IVF treatment In Delhi play a pivotal role in providing these advanced treatment options.

Coping with Infertility 

Battling male infertility and coping with unsuccessful attempts can negatively impact one’s emotional, psychological, and relational well-being. 

Seeking supportive communities, couples counseling, stress management through meditation/yoga, transparency with one’s partner, focusing inward on health gains made so far, and maintaining a hopeful stance also assuage some of the frustrations.

Preventive Care

While several factors causing male infertility might be out of hand, adopting some proactive steps goes a long way:

– Maintaining proper weight and fitness levels

– Avoiding smoking/excessive alcohol consumption

– Reducing exposure to workplace toxins  

– Stress management and restful sleep  

– Regular health check-ups to monitor hormonal levels and sperm quality

By promptly recognizing symptoms and risks early on, many male-linked fertility problems can be managed or reversed successfully.

The Final Thoughts

Our expanding understanding of male reproductive health has brought infertility treatments a long way. Male factor infertility is a complex problem, but seeking timely assistance from fertility specialists regarding suitable diagnosis procedures and customized treatment plans, including ART options, improves one’s likelihood of fathering their own biological child.   

If you and your partner have been struggling to conceive or have any of the symptoms/risk factors discussed here, consult expert doctors specializing in male infertility evaluation and care. 

Healthcare providers like Nandi IVF have extensive experience in fertility treatments, including IVF, ICSI, surgical procedures, and holistic health management based on the underlying infertility causes. Reach out to us at Nandi IVF for comprehensive assistance in diagnosing and overcoming this challenge.

Common Factors That Affect IVF Success Rate

For many couples struggling with infertility, in vitro fertilisation (IVF) offers a lifeline and hope for building their family. However, going through the physical rigours and emotional rollercoaster of IVF treatment is daunting. The financial costs associated with IVF can also be burdensome for some. 

Naturally, patients invest tremendous expectations into each IVF cycle for it to result in the ultimate joy of parenthood. But success rates do vary. As you embark on your IVF journey with Nandi IVF, India’s foremost IVF specialist clinic, it is important to have realistic expectations and understand what common factors can impact IVF success. This blog delves into the crucial elements affecting IVF outcomes and how specialists in Delhi are making a difference.

Factors Influencing IVF Success Rates

Many interlinked factors, ranging from medical to lifestyle issues of both partners, can affect the outcomes in an IVF cycle. Some key parameters are:

Maternal Age 

A woman’s age is the dominant factor determining IVF success. As a woman grows older, especially after 35 years, her ovarian reserve declines, which leads to poorer egg quantity and quality. This directly impacts embryo development and lowers implantation chances. At Nandi IVF, we have achieved high success rates in older patients through optimal protocols.

Cause of Infertility

Issues like damaged fallopian tubes, endometriosis, etc., can decrease IVF success rates compared to unexplained infertility. Our world-class fertility experts are experienced in tackling even complex fertility issues through a customized treatment plan.

Lifestyle Factors

Good lifestyle habits like maintaining a healthy BMI through proper diet and exercise, reducing stress levels, and eliminating smoking/ alcohol improve IVF outcomes.

Protocol and Medications

The type of IVF protocol and medications tailored to suit each patient’s profile by fertility specialists have a major effect on results. At Nandi IVF, our globally trained doctors follow evidence-based practice to design customized regimens for the best chance of IVF success for every patient.

Sperm Health and Morphology

Along with egg quality, the quality of sperm also equally determines IVF success. Low sperm count, inadequate motility, and high DNA fragmentation negatively impact results.

Embryo Quality and Number

A higher number of good-quality embryos available for transfer directly relates to better success odds. Our embryologists are experts in selecting embryos with maximum implantation potential using advanced technologies.

IVF Lab Conditions

World-class infrastructure and strict protocols followed by our lab provide the optimal nurturing environment for embryos outside the body to boost IVF success.

Transfer Technique

A smooth embryo transfer process adhering to precision techniques leads to higher implantation rates. Our clinical team specializes in both simple and complex transfer processes.

Previous Reproductive History and IVF Success

Your past reproductive history, including previous pregnancies or IVF attempts, can offer insights into future IVF success. The Best Ivf In Delhi uses this information to tailor treatment plans, enhancing the likelihood of a positive outcome.

Addressing Medical Conditions

Certain medical conditions can hinder IVF success. The Best IVF Center in Delhi is equipped to manage issues like uterine abnormalities and ovarian dysfunction, utilizing advanced techniques like pre-implantation genetic diagnosis (PGD) to improve success rates.

Fertility Clinic Expertise Matters

Beyond these individual factors related to patients, the expertise and experience of the IVF clinic play a pivotal role in shaping success in this advanced Assisted Reproductive Technology procedure. IVF treatment in Delhi has seen remarkable advancements, with clinics adopting state-of-the-art technologies to improve outcomes. At Nandi IVF, our outstanding success rates across all age groups vouch for our clinical excellence honed over 5500+ IVF procedures:

  • 80% success rate in women below 35 years
  • 60-65% rate for 35-37-year-olds 
  • 50-55% rate in patients above 40 years

Choose the Best IVF Specialist in Delhi NCR

Becoming a parent is an unmatched emotional high. For those struggling with infertility, Nandi IVF offers the best chance at successful conception through IVF. As Delhi NCR’s top-ranked IVF centre, we have consistently delivered high IVF success rates through our patient-centric treatment approach.

To know more about our IVF success rate or fix an appointment, visit us today! Our patient facilitators will be happy to address all your queries regarding your IVF treatment plan or connect you to our fertility specialists.

Ovulation Disorders: Understanding Causes, Symptoms, and Treatments

Ovulation disorder is defined as a range of medical conditions that can affect a woman’s endocrine system. What is an endocrine system? It is a system in the body that regulates our hormones, the ovulation process, or the process the ovary makes an egg during the monthly cycle (menstruation). Affecting 18-25% of couples with infertility in India, ovulation disorders are increasing at an alarming rate. Yes, it is a big problem but everything has a solution. Here, at the Best IVF Center in Delhi, you will get the best facilities to treat ovarian disorders. Now, let’s look into the causes, symptoms, and treatment of Ovarian Disorders.

Infertility and Ovulation Disorders

Ovulation issues are a common cause of infertility in women. During a normal menstrual cycle, the endocrine system secretes chemicals that prepare the body for pregnancy, including gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone (FSH), and luteinizing hormone (LH).

GnRH and FSH are the primary hormones responsible for inducing an egg to develop within a woman’s ovaries. LH promotes the release of the mature egg (ovum) into the fallopian tube, where a man’s sperm can fertilize it.

Many IVF Specialist in Delhi believes that though cycle durations vary, women who ovulate regularly often have a 28-day menstrual cycle during which they ovulate once. Women with hormonal imbalances or deficiencies may have infrequent ovulation and infertility. 

Now let’s talk about some of these disorders and the symptoms associated with them.

Common Ovulation Disorders and Symptoms

The endocrine system is crucial to the menstrual cycle and the process of becoming pregnant. Some drugs, diseases, and lifestyle variables, such as being overweight or underweight, alter hormone levels and can cause irregular hormone production or injury to the ovaries, resulting in an ovulation problem. According to the Best IVF Center in Delhi, the most common symptoms of ovulation disorder are irregular or absent periods and difficulty in becoming pregnant. 

The following are the most common ovulation issues that should be treated most often with the help of the best IVF doctors in Delhi.

Polycystic Ovarian Syndrome (PCOS)

Doctors of the best IVF Center in Delhi and Scientists do not know the specific cause of PCOS, although it is most likely caused by hormonal abnormalities that influence a woman’s androgen (testosterone) levels and insulin sensitivity. Low insulin sensitivity can cause a rise in blood glucose levels and a subsequent increase in testosterone. Multiple cysts formed over time can prevent ovarian follicles from generating mature eggs, and testosterone androgen excess can interrupt ovulation and induce infertility.

Hypothalamic Amenorrhea

FSH and LH are required to achieve pregnancy. During the menstrual cycle, the pituitary gland secretes FSH to tell the ovaries that a follicle needs to develop into an ovum. FSH levels begin to fall as LH levels rise, indicating the release of the freshly developed egg from the follicle. Women with hypothalamic amenorrhea may have irregular or nonexistent ovulation because their bodies lack the nutrition and fat required to transmit hormone signals to the ovaries.

Other Ovulation disorders are premature ovarian failure and menopause. These all disorders can be treated at the best IVF in Delhi. 

Treatment and Diagnosis of Ovarian Disorders

Some ovulation problems can be identified by physical examination, medical history, and menstrual history. Other illnesses, however, require laboratory blood tests to be diagnosed. 

You will get the best treatment for this disorder from the Best IVF Treatment in Delhi. Some of those treatments are – 

  • Doctors will test a woman’s hormone levels based on her symptoms. Once recognized, most ovulation abnormalities can be addressed with lifestyle modifications or medicine.
  • The best IVF doctor in Delhi may propose dietary changes, fertility-inducing drugs that replace missing hormones, or stress reduction.
  • Women with irregular or missing menstruation should consult a fertility expert if they are unable to conceive within 12 months of having unprotected intercourse regularly.

Ready for an Appointment?

If you are experiencing the symptoms described above, you can contact the best IVF center in Delhi, Nandi IVF. They will guide you with all the required guidance and the treatment regimen that you can follow and prevent these Ovarian disorders from affecting your journey of being pregnant.

FAQs

Question 1: How to diagnose Ovarian Disorder?

Answer: The IVF centers of Delhi believe that for diagnosing these disorders, one should go through the FSH (Follicular Stimulating Hormone) screening. This will help in the evaluation of menstrual irregularities, infertility, and hypogonadism.

Question 2: What are the preventive measures for ovarian disorders?

Answer: To prevent ovarian disorders a person should increase their intake of high fiber, and proteins. They should avoid alcohol consumption, exercise regularly, and manage their stress for better health.

Question 3: What are all hormones associated with ovarian disorders?

Answer: When ovulation does not occur, the ovaries may produce several tiny cysts. These cysts produce androgens. Women with PCOS frequently have elevated amounts of androgens.

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